Internships and post-docs

Would you like to join our teams for an internship or a post-doc?

You will find hereafter our current proposals.

Post-doctoral position
Contribution to the metrological traceability of emerging α-emitting radiopharmaceuticals in the framework of the european AlphaMet project (Metrology for Emerging Targeted Alpha Therapies)

Topic
Targeted alpha therapy, radioactivity metrology, ionization chambers, simulation of radiation interactions in matter, half-life measurements
Description of the proposal
The Laboratoire National Henri Becquerel (LNE-LNHB) at CEA/Saclay is the laboratory responsible for the French references in the field of ionizing radiation. The LNHB is involved in the european EPM AlphaMet (Metrology for Emerging Targeted Alpha Therapies) submitted under the Metrology support for Health call (2022) to provide metrological support for clinical and preclinical studies; it began in September 2023 for a total duration of three years. The project comprises four Work Packages (WP) targeting different issues, with WP1 in particular dedicated to activity metrology and nuclear data measurements for imaging and dosimetry. This project aims at improving the metrological traceability of emerging α-emitting radiopharmaceuticals such as ²¹¹At, ²¹²Pb/²¹²Bi, ²¹³Bi, ²²⁵Ac in order to speed up their availability on the market.
The candidate will participate in the various tasks defined as part of the European AlphaMet project in which the LNHB is involved. Radiation-matter simulations will be carried out to study the response of the laboratory’s ionization chambers in various situations concerning:
1. the evolution of the response during the in-growth of the γ-emitting progeny of ²²⁵Ac,
2. the quantification of the influence of the ²¹⁰At impurity in the case of the measurement of ²¹¹At, and
3. the search for a long-lived radionuclide surrogate of ²¹²Pb for the quality control of dose calibrators.
The candidate will also be involved in setting up a new device aimed at improving the linearity of the measurement of half-life with an ionization chamber. During the post-doctoral stay at LNHB, the candidate will interact with the various partners in the AlphaMet project (activity metrology laboratories, hospitals, clinical study centers).

Contract duration
1 year (possible renewal 1 time)

Preferred starting date
1^st semester 2024

Location
CEA Saclay

Candidate profile
The candidate should have a PhD in nuclear physics with a good experience in simulations of radiation interactions in matter using Monte-Carlo codes such as PENELOPE or GEANT4.

Contacts
Christophe BOBIN, Cheick THIAM
DRT/LIST/DIN/SIMRI/LNHB-MA
Bât. 602
CEA-Saclay
91191 Gif-sur-Yvette FRANCE
Phone: +33 1 69 08 29 64, +33 1 69 08 52 47
Email: christophe.bobin@cea.fr, cheick.thiam@cea.fr
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Informations

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